COVID-19 IgG Antibody Test.

This is a fingerstick blood drop test.

ZRT’s COVID-19 IgG S1 Spike Antibody Test is a highly specific laboratory-based test for the antibodies your body makes in response to an infection with the SARS-CoV-2 virus, which is responsible for the disease known as COVID-19.
This test requires an order from a licensed healthcare provider and collection supervision.
Screen Shot 2020-11-25 at 10.58.29
IgG S1 Spike Test (test for possible immunity)
Performing Lab:  ZRT Laboratory
ZRT Laboratory is a CLIA-certified commercial and research laboratory founded in 1998 by breast cancer researcher David Zava, Ph.D.
Type of test:  Assesses IgG antibodies against both the SARS-CoV-2 S1 spike and nucleocapsid proteins. Results are reported separately for the S1 spike and nucleocapsid proteins, which helps confirm true positives and reduce false negatives. 
Collection source:  Fingerstick (dried blood spot)
A fingerstick with small drops of blood placed on a card and allowed to dry (similar to a blood sugar fingerstick for glucometer use).  Collected under the guidance of a healthcare clinician via telemedicine platform.
Wait Time:  3-5 business days

Detailed instructions included

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FDA Required disclaimer
  • This test has not been FDA cleared or approved
  • Negative results do not rule out SARS-CoV-2 infection, particularly in those who have been in contact with the virus. Follow-up testing with a molecular diagnostic should be considered to rule out infection in these individuals
  • Results from antibody testing should not be used as the sole basis to diagnose or exclude SARS-CoV-2 infection or to inform infection status
  • Positive results may be due to past or present infection with non-SARS-CoV-2 coronavirus strains, such as coronavirus HKU1, NL63, OC43, or 229E
ZRT is a CLIA-certified high complexity testing facility with >17 years’ experience working with dried blood spot, and the COVID-19 IgG S1 Spike Antibody Test was stringently validated in-house.
ZRT Laboratory has submitted the COVID-19 IgG S1 Spike Antibody Test for FDA Emergency Use Authorization (EUA).

Frequently asked questions about this Antibody Test

Does this test check to see if I am immune to COVID-19?

Yes. However, to what extent is still unknown. Your immunity may be a lesser resonse to the virus in the future or complete immunity. It is also unknown exactly how long immunity will last.

When should I have this test done?

Natural infection: At least 7 days after end of symptoms since most people recover in 14 days after onset of symptoms OR 20+ days after first syptoms are noticed. Research has shown that nearly everyone with COVID-19 (Coronavirus disease 2019) developed antibodies by day 20 after symptoms. If you test too early, it is possible that the IgG antibody response (seroconversion) may not have occurred yet. After Vaccination: 14 days after vaccination to check that you have made antibodies against the virus. Depending on vaccine, a second injection may be needed to increase antibody response. If a second vaccine is needed, a repeat antibody check can be done 14 days after that injection. Before Vaccination: If you have had or suspect a previous infection of COVID-19, checking antibodies could help you determine the need for the COVID-19 vaccination.

Does a postive antibody test mean I'm a carrier or contagious in any way?

You could be contagious if you test for antibodies early enough to still have an active infection. You should wait until at least 7 days from the end of symptoms.

What is a false negative/false positive antibody result? How likely are they?

A false negative result is when a patient is/was infected by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) but their antibody result is negative, while a false positive result is when a patient has not been infected by SARS-CoV-2 but tests positive for antibodies. False positives are likely caused by past viral infections, while false negatives are due to when the test was taken or if an individual has a weak antibody response. There are no reference specimens to work with currently, so the only way to determine a false positive is to test samples collected in 2019 and earlier (prior to first COVID-19 cases) and to cross compare testing. The gold standard now is to compare antibody results with PCR testing, which is flawed because of the possibility of PCR false negatives (false positives with PCR testing only come from reagent or sample contamination). Sensitivity and specificity testing of our IRB-approved study samples indicate a very low number of potential false positives and false negatives. Running two separate antibody tests as we do for ZRT’s COVID-19 Dual Antibody Test helps confirm true positive/negative antibody results.

If I am positive for antibodies, does that mean I will always be protected from COVID-19?

Currently is it not clear whether detection of IgG antibodies infers immunity to future COVID-19 (Coronavirus disease 2019) infections. Studies have indicated neutralizing ability of IgG antibodies against SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) in animals, but results need to be looked at with caution. Duration of any immunity is still unknown.

Can this test be used to determine the effectiveness of a vaccine?

Yes. As long as the vaccine is developed based on S1 spike protein.

What's included in the kit?

You will receive all the necessary items to perform a fingerstick. Including lancets, alcohol prep pad, gauze, and bandaid. The blood spot card is also included as well as prepaid return packaging and full instructions.

How much does it cost?

The antibody test is $99. You may be able to receive reimbursement from your insurance. You can use Reimbursify for quick and easy filing of claims. Just click on "Get Reimbursed" above our menu.